Runes are read with a few different factors to take into place. Face up; face down; distance from other runes (especially in a casting instead of a lot placement); and the aspect each rune to the rest of them. For this reason, and more, it can take days and/or multiple sittings to read a casting especially when more complex castings are done.
A few notes to further detail. It does not matter what direction they face. A rune facing up is known as a bright-stave. You could say these are the normal meanings. A rune faced down is a murk-stave. These are read in the "negative" meaning. Sometimes you may have a bright that comes out being murk when read because of it's aspect to another rune. And a murk could be bright (though often as how it can become. Think it's dark right now but the sun will come out tomorrow.) Other times with either factor, a rune, bright or murky, could be blocked. This blockage caused by some factor may be represented by another rune.
A lot of divination is by how you interpret the casting or placement. Personally, I have no idea how you should interpret the rune laid on it's side. I can't explain that one to you as how I feel it is may not be fitting for how you feel it to be. For example. I could completely ignore it and you may feel it to be a blockage. I don't want to tell you to ignore something that may be very important.