I am sorry to hear about your bad luck, sometimes its life, we hit a long high or long low, normally we are somewhere in the middle. Don't get discouraged, this won't help. It could be karma if you did something really bad [murder, not cutting someone off in traffic] it could be a rough patch in your life, or it could be a curse. To be safe, cleanse yourself and your home to get rid of any and all negative energy, then cast a protection spell on your home as well as one for yourself. Choose a method that works best for you.
After cleansing and protecting, work on your outlook, just ignore, don't fret thinking there's a curse, this will invite the negative energy back to you and you could unknowingly curse yourself. Once that's all done, you can start casting spells to bring change like a new job. Of course you should be looking now, but in terms of spell casting, getting the negative energy away is the top priority. At this time you might even wish to look into redecorating and/or fung shui to help with energy flow and a new outlook. It isn't mandatory, just an idea to help you think different and ignore the 'curse' idea.