"By nature it is possible for an object to change from one state to another making transformation of items a possibility but highly improbable."
Not exactly true. Most living animals can really only change into one of two things; energy and soil. You can't take this fact and run with it, assuming that this then means that anything can turn into anything. Humans, for example, seem only capable of becoming non-human via death.
The existence of black holes and worm holes is irrelevant to this conversation, as is the constant discovery of new species.
Yes, I know our knowledge is not infinite and absolute. However, none of this is reason to just up and throw what we do know out the window. If we had always thrown away all non-absolute knowledge we never would have developed medicine, sanitation, science, logic, philosophy, and most other things, really.
Magick is a science. It has certain rules that we think are correct. We will adhere to the belief in these rules because absolutely nothing has ever surfaced to dismiss them, and there have been many failed attempts to do so which implies that they are in fact real and accurate. We will disregard belief in these rules once we have proof to their contrary. Groundlessly asserting otherwise is not particularly different from groundlessly asserting that gravity is a myth.