You'll probably get a few different answers for this from different members; I suggest waiting for a few more replies and reading them all before you leap to any sort of conclusion.
The "Will of the universe" is, as far as I understand, roughly analogous to what a Christian might call the Will of God or God's plan. It is the impetus behind what is naturally, and possibly ideally, meant to be.
I don't know if you can truly resist the will of the universe. I know you can -try- but I do not know if you can succeed. What I DO know is that this may very well be the single worst idea in existence.
The universe, the spirit which encompasses all things, has a lot broader and more all-encompassing view than the extremely limited and biased views you and I have. What the universe says is right probably is. What you and I say is right is probably stupid - such is the nature of an unenlightened being.